Peptide Modifications
Peptide modifications are playing more and more important roles in our research, we can change the physical and chemical property of peptide by modifying its structure and active group. Structure modification includes MAPs, cyclizing, stamped peptide etc; Active group modification includes C-terminal modification, N-terminal modification and side-chain group modification etc.
With many years of practical peptide synthesis and research experience, HongTide have developed specific skills and expertise for making modified and difficult-to-synthesize peptides in excellent quality, we can offers hundreds of peptide modifications such as Fluorescence and Dye Labeling Peptides, Cyclic Peptides Synthesis, Phosphopeptides etc. to meet custom peptide requirements. These peptide modifications can be used to create synthetic peptide with the exact conformation for specific applications. Our highly skilled and experienced staff ensures that the most appropriate methods and techniques are selected for each custom peptide project. HongTide are your best choice for producing custom modified peptides on time and on budget. Our peptide modifications services including but not limited to the following:
We manufacture custom peptides with a broad range of flurescent dys such as FITC, CY5, rhB etc.
We offer a full-range of dye-quencher FRET pairs to label your custom peptide.
We can synthesize phosphorylation peptides from one to five phosphorylation sites with high quality and sulfonation peptides as well.
We can manufacture peptides labed with C13, N14, which are widely used at MS and NMR quantitative analysis.
We offer an adaptable platform for the custom synthesis of stapled peptides catering to a variety of biological applications.
We produce disulfide bridged peptides, utilizes stepwise protection or natural folding strategies.
We offer a versatile platform for the synthesis of lactam ring cyclic peptides.
We produce and deliver peptide libraries in a convenient 96-well plate format adapted to high-throughput screening.
Sugar moieties can be incorporated into your custom peptide(s), at single or multiple locations.
We have developed novel methods for the synthesis and purification of hydrophobic peptide modifications.
We can perform site-specific PEGylation at a variety of sites on the peptide for your research.
Peptoids can enhance binding affinities, lower cytotoxicity, better solubility, and increased cell-permeability. We can manufacture large range of peptoids.
Through cooperating with qualified building block suppliers, we can maunfacture peptide with large amount of unnatural amino acids.
We use Lys residues as the scaffolding core to support the formation ≤8 branches with varying or the same peptide sequences.
We can modify many kinds of linkers and spacers to custom peptides such as PEG, Ahx etc.
Cell-Penetrating Peptides (CPPs) is known as protein transduction domains (PTDs), membrane translocating sequences (MTSs) or Trojan peptides.
We can conjugate many metal chelates to custom peptides such as DOTA, NOTA, DTPA, TETA etc.
We have rich experience on insoluble peptide purification which can enhance the success ratio of peptide synthesis.
We has experience in the synthesis of long peptide sequences. We employ a variety of strategies to overcome poor solvation and aggregation.
We can offer full arrange of N-terminal modifications such as D-Biotin, acetyl, azidation etc.
We can offer full arrange of C-terminal modifications such as AMC, pNA, EDDnp etc.