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116P09

H-Glu(Glu-OH)-OH

H-Glu(Glu-OH)-OH

纯度:>95%HPLC
储存条价:-20°C,避光,干燥。

另提供从粗品至98%纯度规格,具体请联系我们! 本产品仅用于科学研究,不得用于人体!

产品详情

Cat#:
116P09
序列(三字母):
H-Glu(Glu-OH)-OH
序列(单字母):
E(E)
别名:
H-γ-Glu-Glu-OH
分子式:
C10H16N2O7
分子量:
276.25
CAS#:
1116-22-9
合成方法:
Synthetic
存储条件:
-20 °C,避光,干燥
应用:
Di- and Tripeptides
产品描述:
H-Glu(Glu-OH)-OH别名H-γ-Glu-Glu-OH,是大脑一个内源性成分。H-Glu(Glu-OH)-OH能够激活小鼠体内N-甲基-D-天冬氨酸(N-methyl-D-aspartate)受体。
参考文献:
1.  Phosphonate and phosphinate analogues of N-acylated gamma-glutamylglutamate. potent inhibitors of glutamate carboxypeptidase II. Tsukamoto T, Flanary JM, Rojas C, Slusher BS, Valiaeva N, Coward JK. Bioorg Med Chem Lett. 2002 Aug 19;12(16):2189-92. PubMed PMID: 12127534.
2.  Increased intra- and extracellular concentrations of gamma-glutamylglutamate and related dipeptides in the ischemic rat striatum: involvement of glutamyl transpeptidase. Orwar O, Li X, Andiné P, Bergström CM, Hagberg H, Folestad S, Sandberg M. J Neurochem. 1994 Oct;63(4):1371-6. PubMed PMID: 7931288.
3.  Endogenous gamma-L-glutamylglutamate is a partial agonist at the N-methyl-D-aspartate receptors in cultured cerebellar granule cells. Varga V, Janáky R, Holopainen I, Oja SS, Akerman KE. Neurochem Res. 1995 Dec;20(12):1471-6. PubMed PMID: 8789610.
4.  Gamma-glutamyl peptides and related amino acids in rat hippocampus in vitro: effect of depolarization and gamma-glutamyl transpeptidase inhibition. Li X, Orwar O, Revesjö C, Sandberg M. Neurochem Int. 1996 Aug;29(2):121-8. PubMed PMID: 8837040.

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