(Pro3)-Gastric Inhibitory Polypeptide (human) -上海鸿肽生物科技有限公司

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147P03

(Pro3)-Gastric Inhibitory Polypeptide (human)

H-Tyr-Ala-Pro-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-His-Gln-Gln-Asp-Phe-Val-Asn-Trp-Leu-Leu-Ala-Gln-Lys-Gly-Lys-Lys-Asn-Asp-Trp-Lys-His-Asn-Ile-Thr-Gln-OH

纯度：>95%HPLC

储存条价：-20°C，避光，干燥。

另提供从粗品至98%纯度规格，具体请联系我们! 本产品仅用于科学研究，不得用于人体！

产品详情

Cat#:

147P03

序列(三字母)：

H-Tyr-Ala-Pro-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-His-Gln-Gln-Asp-Phe-Val-Asn-Trp-Leu-Leu-Ala-Gln-Lys-Gly-Lys-Lys-Asn-Asp-Trp-Lys-His-Asn-Ile-Thr-Gln-OH

序列(单字母)：

YAPGTFISDYSIAMDKIHQQDFVNWLLAQKGKKNDWKHNITQ

别名：

(Pro3)-GIP (human), (Pro3)-Glucose-Dependent Insulinotropic Polypeptide (human), (Pro3) Gastric Inhibitory Peptide (GIP), human

分子式:

C226H338N60O64S

分子量:

4951.6

CAS#:

299898-52-5

合成方法：

Synthetic

存储条件：

-20 °C，避光，干燥

应用：

Diabetes

产品描述：

(Pro3)-Gastric Inhibitory Polypeptide (human) 别名 (Pro3)-GIP (human), (Pro3)-Glucose-Dependent Insulinotropic Polypeptide (human), (Pro3) Gastric Inhibitory Peptide (GIP), human，是 GIP 的一个拮抗剂。

外观英文

White Lyophilisate

参考文献:

1. Chromogranin A: a new proposal for trafficking, processing and induction of granule biogenesis. H.Koshimizu et al., Regul. Pept., 160, 153 (2010)

2. Early administration of the glucose-dependent insulinotropic polypeptide receptor antagonist (Pro3)GIP prevents the development of diabetes and related metabolic abnormalities associated with genetically inherited obesity in ob/ob mice. P.Irwin et al., Diabetologia, 50, 1532 (2007)

3. Chemical ablation of gastric inhibitory polypeptide receptor action by daily (Pro3)GIP administration improves glucose tolerance and ameliorates insulin resistance and abnormalities of islet structure in obesity-related diabetes. V.A.Gault et al., Diabetes, 54, 2436 (2005)

4. Characterization of the cellular and metabolic effects of a novel enzyme-resistant antagonist of glucose-dependent insulinotropic polypeptide. V.A.Gault et al., Biochem. Biophys. Res. Commun., 290, 1420 (2002)

5. Effects of acute and chronic administration of GIP analogues on cognition, synaptic plasticity and neurogenesis in mice. E.Faivre et al., Eur. J. Pharmacol., 674, 294 (2012)

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(Pro3)-Gastric Inhibitory Polypeptide (human)

纯度：>95%HPLC

储存条价：-20°C，避光，干燥。

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